| polymorphism | factor | odds ratio | pvalue | initial number | replication number | Population | age of cases | shorter lived allele | longer lived allele | study type | reference |
| rs429358, rs7412 | APOE | — | 0.025 | (150 m, 74 f) vs (121 m, 320 f) | — | Ashkenazi Jewish | Mean age 75 | e4 | e2 | Candidate Region/Gene | 15621215 |
| rs1800591-rs61733139 | MTTP | — | 0.61 | 197 vs 251 | — | Dutch | Mean age 93.8±3.1 | — | — | Candidate Region/Gene | 16611701 |
| rs1800591-rs61733139 | MTTP | — | 0.46 | 655 vs 244 | — | Dutch | Mean age 87.5±3.1 | — | — | Meta-Analysis | 16611701 |
| rs1800591-rs61733139 | MTTP | — | 0.93 | 164 vs 261 | — | Dutch | Mean age 93.8 ± 3.1 | — | — | Candidate Region/Gene | 16611701 |
| apoE haplotypes | APOE | — | 0.013 | 35 old vs 71 young vs 54 MI patients | — | Chinese | 90+ | apoE4 | — | Candidate Region/Gene | 11780357 |
| apoE haplotypes | APOE | — | 0.013 | 35 old vs 71 young vs 54 MI patients | — | Chinese | 90 | apoE4 | ApT4 | Candidate Region/Gene | 11780357 |
| apoE haplotypes | APOE | — | 0.013 | 35 old vs 71 young vs 54 MI patients | — | Chinese | 90 | apoE4 | — | Candidate Region/Gene | 11780357 |
| rs429358, rs7412 | APOE | — | 0.001 | 179 vs 615 | — | Finn | Mean age 100 | e4 | e2, e3 | Candidate Region/Gene | 8018664 |
| D4a | mtDNA haplogroups | — | 0.05 | 112 vs 96 | — | Japanese | Minimum age 105 | non-D4a | D4a | Complete Mitochondrial Genome | 18545700 |
| rs11279109 - APOB XbaI | APOB | — | 0.001 | 191 (case) vs 53 (initial) | — | Chinese | > 90 baseline, Mean age 97 +/- 3 | — | D - X+ | Candidate Region/Gene | 17393087 |
| APOB XbaI − SI000565Q | APOB | — | 0.006 | 191 (case) vs 53 (initial) | — | Chinese | > 90 baseline, Mean age 97 +/- 3 | X+ - Short | X+ - Medium | Candidate Region/Gene | 17393087 |
| rs11279109 - SI000565Q | APOB | — | 0.05 | 191 (case) vs 53 | — | Chinese | > 90 baseline, Mean age 97 +/- 3 | D - S | D - M | Candidate Region/Gene | 17393087 |
| rs11279109 - APOB XbaI - SI000565Q | APOB | — | 0.044 | 191 (case) vs 53 | — | Chinese | > 90 baseline, Mean age 97 +/- 3 | D - X+ - Short | I - X+ - Medium; D - X- - Long; D - X- - Medium | Candidate Region/Gene | 17393087 |
| C4B1 | C4B | — | 0.05 | 77 (cases) vs 235 | — | Italian | Mean age 101 | — | — | Candidate Region/Gene | 10219002 |
| APOE polymorphism | APOE | — | 0.437 | 1408 cases | — | Brazilian | 69.3 +/- 7.2 | — | — | Candidate Region/Gene | 17934638 |
| Cdx2–GATA haplotypes | VDR | — | 0.05 | 923 | — | Dutch | Mean age 75.7 | GG | GA, AA | Candidate Region/Gene | 21051524 |
| rs1061581 - rs1008438 - rs2227956 | Hsp70Ba | 0.55 | 0.015 | 168 cases | — | Danish | Mean age 92.8 +/- 0.4 | — | G-C-T (haplotype) | Candidate Region/Gene | 20388090 |
| APOE polymorphism | APOE | 0.38 | 0.002 | 200 (cases) vs 539 | — | Italian | >88 | e4 | e2 | Candidate Region/Gene | 21703254 |
| APOE polymorphism - HP1/2 common polymorphism | APOE | — | 0.013 | 200 (cases) vs 539 (initial) | — | Italian | >88 | e4-H2 (haplotype) | — | Candidate Region/Gene | 21703254 |
| HP1/2 common polymorphism | HP | — | 0.05 | 200 (cases) vs 539 (initial) (initial) | — | Italian | >88 | — | — | Candidate Region/Gene | 21703254 |
| APOE polymorphism | APOE | 3.26 | 0.001 | 64 vs 1344 | — | Italian | 100+ | e4 | e2 | Candidate Region/Gene | 16960022 |
| REN polymorphism - mtDNA | mtDNA | 3.27 | 0.006 | 157 | — | Italian | 100+ | — | REN10 - mtDNA haplogroup H | Candidate Region/Gene | 11938442 |
| rs915179-rs2485662-rs4641-rs1468772 | LMNA | 1.56 | 2.5e-05 | 873 vs 443 | New England Centenarian Study (NECS) (N = 738), (ii) the Southern Italian Centenarian Study (SICS) (N = 905), (iii) France (N = 1103), and (iv) the Einstein Ashkenazi Longevity Study (N = 702) | American, Caucasian | Mean age 101.5 | — | GTCT | Candidate Region/Gene | 22340368 |
| APOE haplotype - rs1346044 | APOE | — | 0.0001 | 175 vs 178 | — | Finn | 100.8 | e4 | e2 | Candidate Region/Gene | 10069711 |
| rs2234693 - rs2234693 | ESR1 | — | 0.12 | 108 vs 85 | — | Italian | 90+ | — | — | Candidate Region/Gene | 20819792 |
