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| polymorphism | factor | odds ratio | pvalue | initial number | replication number | Population | age of cases | shorter lived allele | longer lived allele | study type | reference |
|---|---|---|---|---|---|---|---|---|---|---|---|
| rs4340 | ACE | 1.90 | 0.001 | 300 vs 160 | — | French | 100+ | I | D | Candidate Region/Gene | 8136829 |
| APOE e2/e4 | APOE | 2.00 | 0.001 | 300 vs 160 | — | French | 100+ | e4 | e2 | Candidate Region/Gene | 8136829 |
| rs1799752 | ACE | — | 0.025 | 394 vs 238 | — | French | 100.6 years | Insertion | — | Candidate Region/Gene | 9761238 |
| DR7 | HLA-DRB1 | — | 0.01 | 325 centenarians versus 229 nonagenarian siblings | — | French | — | — | — | — | 9425225 |
| DR11 | HLA-DRB1 | — | 0.01 | 325 centenarians versus 229 nonagenarian siblings | — | French | — | — | — | — | 9425225 |
| DR13 | HLA-DRB1 | — | 0.01 | 325 centenarians versus 229 nonagenarian siblings | — | French | — | — | — | — | 9425225 |
| HLA-DRB1 13 generic DRB1 alleles | HLA-DRB1 | 1.72 | 0.01 | 152 vs 2950 | 208 vs original 2950 | French | 100+ and 90+ siblings | non-DR7 alleles | DR7 | Candidate Region/Gene | 9425225 |
| HLA-DRB1 13 generic DRB1 alleles | HLA-DRB1 | 2.03 | 0.001 | 336 vs 2950 | 208 vs original 2950 | French | 100+ and 90+ siblings | non-DR11 alleles | DR11 | Candidate Region/Gene | 9425225 |
| HLA-DRB1 13 generic DRB1 alleles | HLA-DRB1 | 1.46 | 0.01 | 488 vs 2950 | 208 vs original 2950 | French | 100+ and 90+ siblings | non-DR13 alleles | DR13 | Candidate Region/Gene | 9425225 |
| DR7 | HLA-DRB1 | — | 0.01 | 325 centenarians versus 229 nonagenarian siblings | — | French | — | — | — | - | 9425225 |
| DR11 | HLA-DRB1 | — | 0.01 | 325 centenarians versus 229 nonagenarian siblings | — | French | — | — | — | - | 9425225 |
| DR13 | HLA-DRB1 | — | 0.01 | 325 centenarians versus 229 nonagenarian siblings | — | French | — | — | — | - | 9425225 |
| rs1801133 | MTHFR | — | 0.06 | 564 vs. 374 | — | French | mean age 100.71 | TT | CT, CC | Candidate Region/Gene | 9106548 |
| apoAIV(360:His) | APOA4 | — | 0.005 | 119 (see notes) vs 264 | — | French | 74.29 ∓ 8.46 | ApoAIV-1_x000D_, by the order of the sentence - I'm assuming it's Glutamine = G | — | Candidate Region/Gene | 9533408 |
| E2 / E3 / E4 | APOE | — | 1.2e-08 | 560 vs 560 | — | French | centenarians 100th year or beyond, mean age 103.1 | E4 | — | Candidate Region/Gene | 11280044 |