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| polymorphism | factor | odds ratio | pvalue | initial number | replication number | Population | age of cases | shorter lived allele | longer lived allele | study type | reference |
|---|---|---|---|---|---|---|---|---|---|---|---|
| GH1 "intron SNP" | GH1 | — | 0.019 | 866 | — | Dutch | Minimum age 85 | — | — | Candidate Region/Gene | 15771611 |
| Cdx2-GATA haplotype 1 allele | Vitamin D receptor | — | 0.78 | 935 participants | — | Dutch | mean age = 75.7 years | — | — | Candidate Region/Gene | 21051524 |
| rs2060793 | CYP2R1 | — | 0.04 | 1038 vs 461 | — | Dutch | 59.5 years (offspring of nonagerians) | A | — | Candidate Region/Gene | 23128285 |
| rs3829251 | NADSYN1 | — | 0.6 | 1038 vs 461 | — | Dutch | 59.5 years (offspring of nonagerians) | — | — | Candidate Region/Gene | 23128285 |
| Cdx2–GATA haplotypes | VDR | — | 0.05 | 923 | — | Dutch | Mean age 75.7 | GG | GA, AA | Candidate Region/Gene | 21051524 |
| rs2282679 | GC | — | 0.6 | 1038 vs 461 | — | Dutch | 59.5 years (offspring of nonagerians) | — | — | Candidate Region/Gene | 23128285 |
| rs11039149 | NR1H3 | — | 0.015 | 599 | — | Dutch | 85 years | haplotype 1 | haplotype 2 | Candidate Region/Gene | 17452725 |
| rs2069827 | IL6 | — | 0.064 | 1,089 vs 736 | 563 (longtitudinal study) | Danish, Dutch | 92+ Danish, 85+ Dutch | A | — | — | 22234866 |
| rs2802292 | FOXO3A | — | 1.0 | 403 vs 1670 | 4149 vs 7582 | Dutch | mean 94 | — | — | Genome-Wide Association Study | 21418511 |
| rs1800591 | MTTP | — | 0.032 | 525 vs 251 | — | Dutch | Mean age 93.8±3.1 | — | — | Candidate Region/Gene | 16611701 |
| rs1800591 | MTTP | — | 0.64 | 655 vs 244 | — | Dutch | Mean age 87.5±3.1 | — | — | Meta-Analysis | 16611701 |
| rs61733139 | MTTP | — | 0.32 | 525 vs 251 | — | Dutch | Mean age 93.8±3.1 | — | — | Candidate Region/Gene | 16611701 |
| rs1800591-rs61733139 | MTTP | — | 0.61 | 197 vs 251 | — | Dutch | Mean age 93.8±3.1 | — | — | Candidate Region/Gene | 16611701 |
| rs1800591-rs61733139 | MTTP | — | 0.46 | 655 vs 244 | — | Dutch | Mean age 87.5±3.1 | — | — | Meta-Analysis | 16611701 |
| rs2060793 | CYP2R1 | — | 0.04 | 1038 (offspring of nonagenarians who had at least one nonagenarian sibling) vs 461 (offsprings' partners) | — | Dutch | Males: >/= 89; Females: >/= 91 | — | — | Candidate Region/Gene | 23128285 |
| rs61733139 | MTTP | — | 0.57 | 379 vs 251 | — | Dutch | Mean age 93.8 ± 3.1 | — | — | Candidate Region/Gene | 16611701 |
| rs1800591 | MTTP | — | 0.6 | 379 vs 251 | — | Dutch | Mean age 93.8 ± 3.1 | — | — | Candidate Region/Gene | 16611701 |
| rs1800591-rs61733139 | MTTP | — | 0.93 | 164 vs 261 | — | Dutch | Mean age 93.8 ± 3.1 | — | — | Candidate Region/Gene | 16611701 |
| rs61733139 | MTTP | — | 0.43 | 655 vs 244 | — | Dutch | Mean age 87.5±3.1 | — | — | Meta-Analysis | 16611701 |
| rs16861446 | Intergenic | 0.39 | 8.47e-05 | 403 vs 1670 | 3746 vs 5912 | Dutch | Mean age 94 | A | — | Genome-Wide Association Study | 21418511 |
| rs2075650 | TOMM40 | 0.53 | 2.65e-06 | 403 vs 1670 | 3746 vs 5912 | Dutch | Mean age 94 | G | — | Genome-Wide Association Study | 21418511 |
| rs12548622 | Intergenic | 0.54 | 8.78e-06 | 403 vs 1670 | 3746 vs 5912 | Dutch | Mean age 94 | G | — | Genome-Wide Association Study | 21418511 |
| rs4133282 | Intergenic | 0.54 | 2.02e-05 | 403 vs 1670 | 3746 vs 5912 | Dutch | Mean age 94 | A | — | Genome-Wide Association Study | 21418511 |
| rs13248142 | Intergenic | 0.55 | 1.43e-05 | 403 vs 1670 | 3746 vs 5912 | Dutch | Mean age 94 | A | — | Genome-Wide Association Study | 21418511 |
| rs12548929 | Intergenic | 0.55 | 3.52e-05 | 403 vs 1670 | 3746 vs 5912 | Dutch | Mean age 94 | A | — | Genome-Wide Association Study | 21418511 |