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| polymorphism | factor | odds ratio | pvalue | initial number | replication number | Population | age of cases | shorter lived allele | longer lived allele | study type | reference |
|---|---|---|---|---|---|---|---|---|---|---|---|
| HMOX1 (GT)_n repeats | HMOX1 | 0.56 | 0.0027 | 108 vs 154 | — | Japanese | Mean age 80.5 | 33 < repeats | — | Candidate Region/Gene | 12566526 |
| rs9340799 | ESR1 | — | 0.22 | 108 vs 85 | — | Italian | 90+ | — | — | Candidate Region/Gene | 20819792 |
| rs2234693 - rs2234693 | ESR1 | — | 0.12 | 108 vs 85 | — | Italian | 90+ | — | — | Candidate Region/Gene | 20819792 |
| rs2701858, rs9486902 | — | 3.23 | 0.0001 | 1088 | — | Danish | 92+ | — | — | Candidate Region/Gene | 23607278 |
| rs10047589 | TXNRD1 | 1.46 | 0.043 | 1089 (see notes - follow-up study) | 563 (see notes - follow-up study) | Danish | 92.2–93.8 (mean age 93.2) w/ 11.4 years follow-up | G | — | Candidate Region/Gene | 22406557 |
| rs26802 | GHRL | 2.34 | 0.032 | 1089 (see notes - follow-up study) | 563 (see notes - follow-up study) | Danish | 92.2–93.8 (mean age 93.2) w/ 11.4 years follow-up | A | — | Candidate Region/Gene | 22406557 |
| rs13320360 | MLH1 | 3.13 | 0.0036 | 1089 (see notes - follow-up study) | 563 (see notes - follow-up study) | Danish | 92.2–93.8 (mean age 93.2) w/ 11.4 years follow-up | A | — | Candidate Region/Gene | 22406557 |
| rs2509049 | H2AFX | 0.63 | 0.017 | 1089 (see notes - follow-up study) | 563 (see notes - follow-up study) | Danish | 92.2–93.8 (mean age 93.2) w/ 11.4 years follow-up | A | — | Candidate Region/Gene | 22406557 |
| rs705649 | XRCC5 | — | 0.029 | 1089 (see notes - follow-up study) | 563 (see notes - follow-up study) | Danish | 92.2–93.8 (mean age 93.2) w/ 11.4 years follow-up | A - Unsure | — | Candidate Region/Gene | 22406557 |
| rs207444 | XDH | — | 0.046 | 1089 (see notes - follow-up study) | 563 (see notes - follow-up study) | Danish | 92.2–93.8 (mean age 93.2) w/ 11.4 years follow-up | G - Unsure | — | Candidate Region/Gene | 22406557 |
| rs9486902 | FOXO3 | 1.40 | 0.0118 | 1089 vs 736 | — | Danish | 92–93 | C | — | Candidate Region/Gene | 20849522 |
| rs12206094 | FOXO3 | 1.38 | 0.0076 | 1089 vs 736 | — | Danish | 92–93 | C | — | Candidate Region/Gene | 20849522 |
| rs2802292 | FOXO3 | 1.34 | 0.0078 | 1089 vs 736 | — | Danish | 92–93 | T | — | Candidate Region/Gene | 20849522 |
| rs13220810 | FOXO3 | 0.75 | 0.0223 | 1089 vs 736 | — | Danish | 92–93 | C | — | Candidate Region/Gene | 20849522 |
| rs3800231 | FOXO3 | 1.26 | 0.0495 | 1089 vs 736 | — | Danish | 92–93 | G | — | Candidate Region/Gene | 20849522 |
| rs13251813 | WRN | 1.84 | 0.0002 | 1089 vs 736 | 1613 vs 1104 | Danish | 92.2–93.8 (mean age 93.2 | G | — | Candidate Region/Gene | 22406557 |
| rs1207362 | KL | 0.63 | 0.0001 | 1089 vs 736 | 1613 vs 1104 | Danish | 92-93 years old | A | C | Candidate Region/Gene | 22406557 |
| rs2267723 | GHRHR | 0.70 | 0.0001 | 1089 vs 736 | 1613 vs 1104 | Danish | 92-93 years old | G | A | Candidate Region/Gene | 22406557 |
| rs3842755 | INS | 1.79 | 0.0001 | 1089 vs 736 | 1613 vs 1104 | Danish | 92-93 years old | C | A | Candidate Region/Gene | 22406557 |
| rs572169 | GHSR | 0.72 | 0.0045 | 1089 vs 736 | 1613 vs 1104 | Danish | 92-93 years old | A | G | Candidate Region/Gene | 22406557 |
| rs9456497 | IGF2R | 1.42 | 0.005 | 1089 vs 736 | 1613 vs 1104 | Danish | 92-93 years old | A | G | Candidate Region/Gene | 22406557 |
| rs11571461 | RAD52 | 2.23 | 0.0001 | 1089 vs 736 | 1613 vs 1104 | Danish | 92-93 years old | A | G | Candidate Region/Gene | 22406557 |
| rs13251813 | WRN | 1.84 | 0.0002 | 1089 vs 736 | 1613 vs 1104 | Danish | 92-93 years old | G | A | Candidate Region/Gene | 22406557 |
| rs1805329 | RAD23B | 0.72 | 0.0309 | 1089 vs 736 | 1613 vs 1104 | Danish | 92-93 years old | A | G | Candidate Region/Gene | 22406557 |
| rs2953983 | POLB | 1.60 | 0.0225 | 1089 vs 736 | 1613 vs 1104 | Danish | 92-93 years old | A | G | Candidate Region/Gene | 22406557 |