| polymorphism | factor | odds ratio | pvalue | initial number | replication number | Population | age of cases | shorter lived allele | longer lived allele | study type | reference |
| CYP2D6*3 | CYP2D6 | — | 1.0 | 552 vs 243 | — | French | mean 101 | — | — | Candidate Region/Gene | 9654200 |
| CYP2D6*4 | CYP2D6 | — | 1.0 | 523 vs 252 | — | French | mean 101 | — | — | Candidate Region/Gene | 9654200 |
| GSTM1 deletion | GSTM1 | — | 1.0 | 565 vs 229 | — | French | mean 101 | — | — | Candidate Region/Gene | 9654200 |
| NAT2*5A (C 481 T), NAT2*6A (G 590 A), NAT2*7A (G 857 A), and NAT2*14A (G 191 A) | NAT2 | — | 1.0 | 188 vs 88 | — | French | mean 101 | — | — | Candidate Region/Gene | 9654200 |
| - | HRAS1 | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | 1 (specifically for SIRT3 in a French population) | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
| rs4073590 | DEAF1 | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
| rs11040489 | KRTAP5-6 | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
| rs800140 | TSPAN32 | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
| - | INS | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
