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polymorphism factor odds ratio pvalue initial number replication number Population age of cases shorter lived allele longer lived allele study type reference
MTP -493G/T MTP — 0.854 — — Chinese — — — - 23273182
microsatellite polymorphism surrounded by rs2288377, rs5742612, and rs35767 IGF1 — 0.922 493 vs 425 — Chinese (females ≥ 94; males ≥ 90 — — Candidate Region/Gene 20199671
FOXO3A, various FOXO3 1.67 0.0002 760 vs 1060 — Chinese 100+ — — Candidate Region/Gene 20884733
HLA-A phenotype HLA-A 1.95 0.002 201 vs 211 — Chinese 22 centenarians + 179 nonagenarians (mean age 93 ±1.04) A9 A30 Candidate Region/Gene 9147371
rs429358 + rs7412 APOE — 0.04 1236 vs 326 — Chinese 60+ e4 non-e4 Candidate Region/Gene 9792194
rs4746720 — 1.35 0.022 246 vs 236 — Chinese 60-90 — C Candidate Region/Gene 20633545
rs3758391 SIRT1 1.45 0.026 246 vs 236 — Chinese 60-90 — C Candidate Region/Gene 20633545
rs3758391 SIRT1 1.45 0.026 246 vs 236 — Chinese 71.2±7.1 years T — Candidate Region/Gene 20633545
rs4746720 SIRT1 1.35 0.022 246 vs 236 — Chinese 71.2±7.1 years T — Candidate Region/Gene 20633545
5178 adenine/cytosine ND2 — 0.363 95 vs 298 — Chinese 76.2±5.0 C — Candidate Region/Gene 12384792
apoE haplotypes APOE — 0.013 35 old vs 71 young vs 54 MI patients — Chinese 90 apoE4 ApT4 Candidate Region/Gene 11780357
apoE haplotypes APOE — 0.013 35 old vs 71 young vs 54 MI patients — Chinese 90 apoE4 — Candidate Region/Gene 11780357
E4 APOE — 0.013 35 vs 125 — Chinese 90 years or over — — Candidate Region/Gene 11780357
APOE4 APOE — 0.013 35 vs 125 — Chinese 90 years or over High E4 frequency — Candidate Region/Gene 11780357
apoE haplotypes APOE — 0.013 35 old vs 71 young vs 54 MI patients — Chinese 90+ apoE4 — Candidate Region/Gene 11780357
9 mtDNA haplogroups mtDNA haplogroup 0.38 0.025 98 vs. 117 — Chinese 90-100 years old J non-J - 18759861
C150T mtDNA L2 — 1.0 556 vs. 403 — Chinese 90-108 — — Mitochondrial Haplogroup 21262335
mt146 C>T — — 0.005 113 (cases) vs 200 — Chinese 90-110 mt146T mt146C Complete Mitochondrial Genome 22729909
rs2853826 MT-ND3 — 0.219 98 vs 117 — Chinese 90–100 A — Candidate Region/Gene 18759861
Haplogroup J — 0.38 0.025 98 vs 117 — Chinese 90–100 — — Candidate Region/Gene 18759861
rs3928306 MT-RNR2 0.49 0.027 98 vs 117 — Chinese 90–100 A — Candidate Region/Gene 18759861
rs28359172 MT-ND5 0.30 0.003 98 vs 117 — Chinese 90–100 G — Candidate Region/Gene 18759861
mtDNA C150T — — 0.936 556 vs 403 — Chinese 90–108 (94.59±3.34) — — Candidate Region/Gene 21262335
rs2288377 IGF1 — 1.0 485 vs 392 — Chinese 94.92 — — Candidate Region/Gene 18761080
rs5742612 IGF1 — 1.0 485 vs 392 — Chinese 94.92 — — Candidate Region/Gene 18761080
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  • 25 of 104 variants