| polymorphism | factor | odds ratio | pvalue | initial number | replication number | Population | age of cases | shorter lived allele | longer lived allele | study type | reference |
| rs3176343-rs3176344-rs3176349-rs1801270 | CDKN1A | — | 0.9852 | 184 vs 184 | — | Italian | 100 | — | — | Candidate Region/Gene | 20126416 |
| 9824C,10400T | mtDNA | — | 0.955 | 463 vs 1389 | — | Chinese | >/=95 | — | — | Mitochondrial Haplogroup | 19641616 |
| 4833G,14569A,10400T | mtDNA | — | 0.949 | 463 vs 1389 | — | Chinese | >/=95 | — | — | Mitochondrial Haplogroup | 19641616 |
| rs1800591-rs61733139 | MTTP | — | 0.93 | 164 vs 261 | — | Dutch | Mean age 93.8 ± 3.1 | — | — | Candidate Region/Gene | 16611701 |
| 7196A,10400T | mtDNA | — | 0.847 | 463 vs 1389 | — | Chinese | >/=95 | — | — | Mitochondrial Haplogroup | 19641616 |
| rs3176343-rs3176344-rs3176349-rs1801270-rs1059234-rs876581 | CDKN1A | — | 0.8 | 184 vs 184 | — | Italian | 100 | — | — | Candidate Region/Gene | 20126416 |
| 14569A,10400T | mtDNA | — | 0.796 | 463 vs 1389 | — | Chinese | >/=95 | — | — | Mitochondrial Haplogroup | 19641616 |
| 14979C,3010A,5178A,10400T | mtDNA | — | 0.781 | 463 vs 1389 | — | Chinese | >/=95 | — | — | Mitochondrial Haplogroup | 19641616 |
| 10646A,10400T | mtDNA | — | 0.753 | 463 vs 1389 | — | Chinese | >/=95 | — | — | Mitochondrial Haplogroup | 19641616 |
| rs1800591-rs61733139 | MTTP | — | 0.61 | 197 vs 251 | — | Dutch | Mean age 93.8±3.1 | — | — | Candidate Region/Gene | 16611701 |
| 12811C,9824C,10400T | mtDNA | — | 0.587 | 463 vs 1389 | — | Chinese | >/=95 | — | — | Mitochondrial Haplogroup | 19641616 |
| 1107C,5178A,10400T | mtDNA | — | 0.559 | 463 vs 1389 | — | Chinese | >/=95 | — | — | Mitochondrial Haplogroup | 19641616 |
| 9296T,8964T,8020A,3010A,5178A,10400T | mtDNA | — | 0.55 | 463 vs 1389 | — | Chinese | >/=95 | — | — | Mitochondrial Haplogroup | 19641616 |
| 8020A,3010A,5178A,10400T | mtDNA | — | 0.549 | 463 vs 1389 | — | Chinese | >/=95 | — | — | Mitochondrial Haplogroup | 19641616 |
| 13263G,7196A,10400T | mtDNA | — | 0.485 | 463 vs 1389 | — | Chinese | >/=95 | — | — | Mitochondrial Haplogroup | 19641616 |
| rs1800591-rs61733139 | MTTP | — | 0.46 | 655 vs 244 | — | Dutch | Mean age 87.5±3.1 | — | — | Meta-Analysis | 16611701 |
| 8684T,7196A,10400T | mtDNA | — | 0.457 | 463 vs 1389 | — | Chinese | >/=95 | — | — | Mitochondrial Haplogroup | 19641616 |
| APOE polymorphism | APOE | — | 0.437 | 1408 cases | — | Brazilian | 69.3 +/- 7.2 | — | — | Candidate Region/Gene | 17934638 |
| 13590A,9bp-deletion,10873T | mtDNA | — | 0.43 | 463 vs 1389 | — | Chinese | >/=95 | — | — | Mitochondrial Haplogroup | 19641616 |
| 5178A,10400T | mtDNA | — | 0.387 | 463 vs 1389 | — | Chinese | >/=95 | — | — | Mitochondrial Haplogroup | 19641616 |
| 15662G,8584A,9bp-deletion,10873T | mtDNA | — | 0.357 | 463 vs 1389 | — | Chinese | >/=95 | — | — | Mitochondrial Haplogroup | 19641616 |
| HP*1 F/S | HP | 0.82 | 0.33 | 1072 total | — | Italian | >88 | — | — | Candidate Region/Gene | 21147083 |
| 8964T,8020A,3010A,5178A,10400T | mtDNA | — | 0.319 | 463 vs 1389 | — | Chinese | >/=95 | — | — | Mitochondrial Haplogroup | 19641616 |
| 9bp-deletion,10873T | mtDNA | — | 0.311 | 463 vs 1389 | — | Chinese | >/=95 | — | — | Mitochondrial Haplogroup | 19641616 |
| 12406A,3970T,12705C,10873T | mtDNA | — | 0.304 | 463 vs 1389 | — | Chinese | >/=95 | — | — | Mitochondrial Haplogroup | 19641616 |
