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polymorphism | factor | odds ratio | pvalue | initial number | replication number | Population | age of cases | shorter lived allele | longer lived allele | study type | reference |
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DR7 | HLA-DRB1 | — | 0.01 | 325 centenarians versus 229 nonagenarian siblings | — | French | — | — | — | - | 9425225 |
DR11 | HLA-DRB1 | — | 0.01 | 325 centenarians versus 229 nonagenarian siblings | — | French | — | — | — | - | 9425225 |
DR13 | HLA-DRB1 | — | 0.01 | 325 centenarians versus 229 nonagenarian siblings | — | French | — | — | — | - | 9425225 |
rs1776180 | EXO1 | 1.39 | 0.01 | 395 vs 411 | 455 vs 109 | French, German | Mean age 101.3 | G | C | Candidate Region/Gene | 19698732 |
apoAIV(360:His) | APOA4 | — | 0.005 | 119 (see notes) vs 264 | — | French | 74.29 ∓ 8.46 | ApoAIV-1_x000D_, by the order of the sentence - I'm assuming it's Glutamine = G | — | Candidate Region/Gene | 9533408 |
HLA-DRB1 13 generic DRB1 alleles | HLA-DRB1 | 2.03 | 0.001 | 336 vs 2950 | 208 vs original 2950 | French | 100+ and 90+ siblings | non-DR11 alleles | DR11 | Candidate Region/Gene | 9425225 |
rs4340 | ACE | 1.90 | 0.001 | 300 vs 160 | — | French | 100+ | I | D | Candidate Region/Gene | 8136829 |
APOE e2/e4 | APOE | 2.00 | 0.001 | 300 vs 160 | — | French | 100+ | e4 | e2 | Candidate Region/Gene | 8136829 |
E2 / E3 / E4 | APOE | — | 1.2e-08 | 560 vs 560 | — | French | centenarians 100th year or beyond, mean age 103.1 | E4 | — | Candidate Region/Gene | 11280044 |