Denigma Buck Institute Health Extension

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polymorphism factor odds ratio pvalue initial number replication number Population age of cases shorter lived allele longer lived allele study type reference
rs662 PON1 — 1.0 579 vs 308 — Italian Over 100 G A Candidate Region/Gene 12082503
rs854560 PON1 — 1.0 579 vs 308 — Italian Over 100 — — Candidate Region/Gene 12082503
codon 192 PON1 — 1.0 192 vs 77 — Italian 56 ages 66 to 89, 96 >90 — — Candidate Region/Gene 16799134
codon 55 PON1 — 1.0 192 vs 77 — Italian 56 ages 66 to 89, 96 >90 — — Candidate Region/Gene 16799134
rs1800629 TNF — 1.0 174 vs 224 — Italian >100 — — Candidate Region/Gene 12676903
SV-6 CLU — 1.0 49 vs 27 vs 20 — Greek, Italian 99–107 — — Candidate Region/Gene 16804001
rs5182 AGTR1 0.97 1.0 173 vs 376 — Italian 99-106 (mean 100.9±1.7) — — Candidate Region/Gene 22569962
rs5183 AGTR1 0.27 1.0 173 vs 376 — Italian 99-106 (mean 100.9±1.7) — — Candidate Region/Gene 22569962
rs7843014 PTK2 — 1.0 79 vs 316 — Italian 100-104 — — Candidate Region/Gene 24930376
rs7460 PTK2 — 1.0 79 vs 316 — Italian 100-104 — — Candidate Region/Gene 24930376
rs3825075 SIRT3 — 1.0 668 — Italian 70+ — — Candidate Region/Gene 23839864
rs3176343-rs3176344-rs3176349-rs1801270 CDKN1A — 0.9852 184 vs 184 — Italian 100 — — Candidate Region/Gene 20126416
rs3829963 CDKN1A 0.99 0.969 184 vs 184 — Italian 100 — — Candidate Region/Gene 20126416
rs9470367 CDKN1A 1.01 0.949 184 vs 184 — Italian 100 — — Candidate Region/Gene 20126416
rs5189 AGTR1 0.75 0.945 173 vs 376 — Italian 99-106 (mean 100.9±1.7) — — Candidate Region/Gene 22569962
rs6457931 CDKN1A 1.01 0.936 184 vs 184 — Italian 100 — — Candidate Region/Gene 20126416
rs4151702 CDKN1A 1.02 0.93 184 vs 184 — Italian 100 — — Candidate Region/Gene 20126416
rs12721225 AGTR1 0.37 0.929 173 vs 376 — Italian 99-106 (mean 100.9±1.7) — — Candidate Region/Gene 22569962
rs733590 CDKN1A 0.97 0.875 184 vs 184 — Italian 100 — — Candidate Region/Gene 20126416
rs5186 AGTR1 1.15 0.875 173 vs 376 — Italian 99-106 (mean 100.9±1.7) — — Candidate Region/Gene 22569962
rs730506 CDKN1A 0.96 0.852 184 vs 184 — Italian 100 — — Candidate Region/Gene 20126416
rs1042522 TP53 — 0.85 66 vs 150 — Italian 100.19±2.2 (95-105) — — Candidate Region/Gene 15195682
?145K LMP7 — 0.849 157 vs 311 — Italian 88+ K — Candidate Region/Gene 11772516
rs10277237 — — 0.805 321 vs 442 — Italian 89-107 — — Candidate Region/Gene 23572278
rs3176343-rs3176344-rs3176349-rs1801270-rs1059234-rs876581 CDKN1A — 0.8 184 vs 184 — Italian 100 — — Candidate Region/Gene 20126416
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