| polymorphism | factor | odds ratio | pvalue | initial number | replication number | Population | age of cases | shorter lived allele | longer lived allele | study type | reference |
| - | HRAS1 | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | 1 (specifically for SIRT3 in a French population) | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
| - | SIRT3 | — | 0.145 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
| - | TH | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
| - | INS | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
| - | IGF2 | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
| rs4073591 | — | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
| rs4073590 | DEAF1 | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
| rs11040489 | KRTAP5-6 | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
| rs4930001 | — | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
| rs800140 | TSPAN32 | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
| rs16928120 | — | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
| GSTM1 deletion | GSTM1 | — | 1.0 | 565 vs 229 | — | French | mean 101 | — | — | Candidate Region/Gene | 9654200 |
| rs1801133 | MTHFR | — | 0.06 | 564 vs. 374 | — | French | mean age 100.71 | TT | CT, CC | Candidate Region/Gene | 9106548 |
| I/D (insertion/deletion) | ACE | — | 0.33 | 560 vs 560 | — | French | centenarians 100th year or beyond, mean age 103.1 | — | — | Candidate Region/Gene | 11280044 |
| E2 / E3 / E4 | APOE | — | 1.2e-08 | 560 vs 560 | — | French | centenarians 100th year or beyond, mean age 103.1 | E4 | — | Candidate Region/Gene | 11280044 |
| CYP2D6*3 | CYP2D6 | — | 1.0 | 552 vs 243 | — | French | mean 101 | — | — | Candidate Region/Gene | 9654200 |
| CYP2D6*4 | CYP2D6 | — | 1.0 | 523 vs 252 | — | French | mean 101 | — | — | Candidate Region/Gene | 9654200 |
| HLA-DRB1 13 generic DRB1 alleles | HLA-DRB1 | 1.46 | 0.01 | 488 vs 2950 | 208 vs original 2950 | French | 100+ and 90+ siblings | non-DR13 alleles | DR13 | Candidate Region/Gene | 9425225 |
| rs1776180 | EXO1 | 1.39 | 0.01 | 395 vs 411 | 455 vs 109 | French, German | Mean age 101.3 | G | C | Candidate Region/Gene | 19698732 |
| rs1799752 | ACE | — | 0.025 | 394 vs 238 | — | French | 100.6 years | Insertion | — | Candidate Region/Gene | 9761238 |
| HLA-DRB1 13 generic DRB1 alleles | HLA-DRB1 | 2.03 | 0.001 | 336 vs 2950 | 208 vs original 2950 | French | 100+ and 90+ siblings | non-DR11 alleles | DR11 | Candidate Region/Gene | 9425225 |
| DR7 | HLA-DRB1 | — | 0.01 | 325 centenarians versus 229 nonagenarian siblings | — | French | — | — | — | — | 9425225 |
| DR11 | HLA-DRB1 | — | 0.01 | 325 centenarians versus 229 nonagenarian siblings | — | French | — | — | — | — | 9425225 |
| DR13 | HLA-DRB1 | — | 0.01 | 325 centenarians versus 229 nonagenarian siblings | — | French | — | — | — | — | 9425225 |
| DR7 | HLA-DRB1 | — | 0.01 | 325 centenarians versus 229 nonagenarian siblings | — | French | — | — | — | - | 9425225 |
