Symbol: HSPA1L Name: heat shock 70kDa protein 1-like Entrez gene ID: 3305 Ensembl gene ID: ENSG00000204390 Species: Human (Taxid: 9606) Observation: The frequency of the T2437C transversion (Met to Thr) polymorphism in the HSPA1L gene was investigated in a healthy aged population of 100 control samples (59% female, 41% male with an age-range of 19-45 years) and 129 aged consecutive samples (70% female, 30% male with an age range of 80-97 years). The 2437T polymorphic nucleotide was observed to increase in the elderly, although not attaining statistical significance. The TT genotype was observed to be significantly increased within the aged population, while conversely the TC genotype was significantly decreased in the aged subjects [12742533].HSPA1L was found to be associated with longevity [12742533]. HSPA1L was found to be associated with longevity [16804002]. HSPA1L was found to be associated with longevity [16804002]. Assays: Organismal Lifespan Longevity Associated Variants: Classification: Type: References: Aging Relevance Analysis/Source: Homologs Edit \ Update (Admin) | Delete |
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