| polymorphism | factor | odds ratio | pvalue | initial number | replication number | Population | age of cases | shorter lived allele | longer lived allele | study type | reference |
| 56 SNPs - CYP2C gene family | CYP2C gene family: CYP2C8, CYP2C9, CYP2C18, CYP2C19 | — | 1.0 | 1,384 vs 945 | — | German | Mean age 98.8 | — | — | Candidate Region/Gene | 21798861 |
| rs3758391 | SIRT1 | — | 1.0 | 386 vs 640 vs 547 | — | German | Mean age 101 | — | — | Candidate Region/Gene | 16257164 |
| rs1885472 | SIRT1 | — | 1.0 | 386 vs 640 vs 547 | — | German | Mean age 101 | — | — | Candidate Region/Gene | 16257164 |
| rs2273773 | SIRT1 | — | 1.0 | 386 vs 640 vs 547 | — | German | Mean age 101 | — | — | Candidate Region/Gene | 16257164 |
| rs10997870 | SIRT1 | — | 1.0 | 386 vs 640 vs 547 | — | German | Mean age 101 | — | — | Candidate Region/Gene | 16257164 |
| rs2234975 | SIRT1 | — | 1.0 | 386 vs 640 vs 547 | — | German | Mean age 101 | — | — | Candidate Region/Gene | 16257164 |
| rs1801274 | FCGR2A | — | 1.0 | 408 vs 446 vs 454 | — | German | Centenarians | — | — | Candidate Region/Gene | 16893392 |
| rs4986790 | TLR4 | — | 0.61 | 273 vs 594 | — | German | Mean age 97.9 | — | — | Candidate Region/Gene | 17493663 |
| - | HRAS1 | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | 1 (specifically for SIRT3 in a French population) | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
| - | SIRT3 | — | 0.145 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
| - | TH | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
| - | INS | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
| - | IGF2 | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
| rs4073591 | — | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
| rs4073590 | DEAF1 | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
| rs11040489 | KRTAP5-6 | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
| rs4930001 | — | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
| rs800140 | TSPAN32 | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
| rs16928120 | — | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
| rs11188059 | CYP2C | — | 0.04 | 616 centenarians versus control group of 945 younger individuals | — | German | — | — | — | Candidate Region/Gene | 21798861 |
| rs2071069 | TPI1 | — | 0.05 | 1422 vs 967 | — | German | mean age: 98.8, age range: 95–110 | (SNP is G/A) | — | Candidate Region/Gene | 18510744 |
| rs2071065 | TPI1 | — | 0.05 | 1422 vs 967 | — | German | mean age: 98.8, age range: 95–110 | (SNP is T/C) | — | Candidate Region/Gene | 18510744 |
| rs770087 | DUSP6 | 1.53 | 0.002 | 386 vs 410 | 541 vs 469 | German | 100 to 110, mean age = 101.3 | C | — | Candidate Region/Gene | 20800603 |
| rs2301582 | NALP1 | 1.30 | 0.011 | 386 vs 410 | 541 vs 469 | German | 100 to 110, mean age = 101.3 | C | — | Candidate Region/Gene | 20800603 |
| rs648802 | PERP | 1.29 | 0.012 | 386 vs 410 | 541 vs 469 | German | 100 to 110, mean age = 101.3 | C | — | Candidate Region/Gene | 20800603 |
