Longevity Variant Database

Narrow results by variant, study, or associated fields (e.g. gene symbol ADRB2):

Use ontology terms to further narrow results (e.g. aging, insulin, etc.):


  • Variant effect: + -
  • Variant type: + -

  • 1 2 3 4 5 6 7 8 9 10 11 12
    13 14 15 16 17 18 19 20 21 X Y MT
    Export results (Download)

    Populations | Study Types | Variant Types



    LVDB_word_cloud.png
    logo.png
    variants.jpg
    polymorphism factor odds ratio pvalue initial number replication number Population age of cases shorter lived allele longer lived allele study type reference
    rs4537545 IL6R 3e-18 308 American, European, Ashkenazi Jewish 75.7 Candidate Region/Gene 19249341
    rs1528753 8.1e-08 1345 cohort + 1087 offspring American Genome-Wide Association Study 17903295
    rs3129046 0.66 2.21e-07 763 vs 1085 754 vs 850 German Mean age 99.7 Genome-Wide Association Study 21740922
    rs1610742 0.66 3.02e-07 763 vs 1085 754 vs 850 German Mean age 99.7 Genome-Wide Association Study 21740922
    HRAS1 LASS1 (CGT) APOE 6.91e-07 204 vs 251 American Candidate Region/Gene 20569235
    HRAS1 LASS1 (CGT) APOE 1e-06 79 vs 88 American Candidate Region/Gene 20569235
    rs10493513 1.5e-06 1345 cohort + 1087 offspring American Genome-Wide Association Study 17903295
    rs1610601 0.68 1.98e-06 763 vs 1085 754 vs 850 German Mean age 99.7 Genome-Wide Association Study 21740922
    rs2338013 0.67 2.07e-06 763 vs 1085 754 vs 850 German Mean age 99.7 Genome-Wide Association Study 21740922
    rs4574762 0.19 2.29e-06 410 vs 553 Italian 90–109 Genome-Wide Association Study 21612516
    rs2371208 2.6e-06 1345 cohort + 1087 offspring American Genome-Wide Association Study 17903295
    rs10493514 2.8e-06 1345 cohort + 1087 offspring American Genome-Wide Association Study 17903295
    rs6504441 PRKCA 0.60 2.87e-06 410 vs 553 Italian 90–109 Genome-Wide Association Study 21612516
    rs12413082 MSRB2 0.53 3.33e-06 410 vs 553 Italian 90–109 Genome-Wide Association Study 21612516
    rs1633063 0.68 3.82e-06 763 vs 1085 754 vs 850 German Mean age 99.7 Genome-Wide Association Study 21740922
    rs3129063 0.67 4.33e-06 763 vs 1085 754 vs 850 German Mean age 99.7 Genome-Wide Association Study 21740922
    rs513154 IMPG2 0.52 4.65e-06 410 vs 553 Italian 90–109 Genome-Wide Association Study 21612516
    rs1582594 1.87 4.76e-06 410 vs 553 Italian 90–109 Genome-Wide Association Study 21612516
    rs158869 1.37 4.98e-06 763 vs 1085 754 vs 850 German Mean age 99.7 Genome-Wide Association Study 21740922
    rs350450 0.69 6.34e-06 763 vs 1085 754 vs 850 German Mean age 99.7 Genome-Wide Association Study 21740922
    rs10923806 2.30 7.24e-06 410 vs 553 Italian 90–109 Genome-Wide Association Study 21612516
    HRAS1 LASS1 (CGT) APOE 9e-06 19 vs 73 Georgian Candidate Region/Gene 20569235
    rs29228 0.68 9.12e-06 763 vs 1085 754 vs 850 German Mean age 99.7 Genome-Wide Association Study 21740922
    rs1575892 0.45 9.32e-06 763 vs 1085 754 vs 850 German Mean age 99.7 Genome-Wide Association Study 21740922
    HRAS1 LASS1 (CCT) APOE 1e-05 128 vs 115 Georgian Candidate Region/Gene 20569235
    • Page 1 of 22
    • 25 of 543 variants

    The Longevity Variant Database (LVDB) is a collaborative effort to catalogue all published genetic variants relevant to human longevity.

    The project is directed by the Health Extension Research Foundation [http://www.healthextension.co/about/], and the online content is managed by the members of the Global Computing Initiative.

    LVDB is driven by an international collaboration of scientists, programmers, and volunteers, including Joe Betts-LaCroix, Kristen Fortney, Daniel Wuttke, Eric K. Morgen, Nick Schaum, John M. Adams, Jessica Choi, Barry Goldberg, Amir Levine, Maria Litovchenko, Aiste Narkeviciute, Emily Quist, Navneet Ramesh, Justin Rebo, Dmitri Shytikov, and Jimi Vyas. o


    Suggest a new study Report a database issue