• Species: + -
  • name effect species mean median maximum
    isp-1 mutation A missense mutation in isp-1 leads to low oxygen consumption, decreased sensitivity to reactive oxygen species, and increased mean (60%) and maximum (100%) lifespan. An isp-1;daf-2 double mutant has a lifespan that is longer than either single mutant, but the lifespan extension of the double mutant is not addative relative to each single mutant [11709184]. Worm +60 +100
    • 1 intervention
    Interventions are an extension of GenAge and GenDR.