Denigma

Naam overexpression

Species: Fruit fly (Taxid: 7227)
Factor: Naam
Manipulation: Gain-of-Function, Overexpression
Effect:

Naam overexpression increases mean and maximum lifespan by 30% in both females and males. The lifespan extension is reversed by Sir2 mutants, indicating the it is dependent on Sir2 [18678867].

Mean: +30
Maximum: +30

References:
  • 18678867: Life span extension and neuronal cell protection by Drosophila nicotinamidase.


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

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