mir-239 overexpression

Species: Nematode (Taxid: 6239)
Factor: mir-239
Manipulation: Gain-of-Function, Overexpression
Effect:

Overexpressing mir-239 decreases mean and maximum lifespan by 13 and 17 - 33%, respectively [21129974].

Mean: -13
Maximum: -17 to -33

References:
  • 21129974: MicroRNAs both promote and antagonize longevity in C. elegans.


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR
  • Comparisons:
  • mir-239(OE) vs. control ( 20°C ) : -13.3(mean) -25(max)
  • mir-239(OE) vs. control ( 20°C ) : -13.3(mean) -16.7(max)
  • mir-239(OE) vs. control ( 20°C ) : -13.3(mean) -33.3(max)



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