Denigma

CYR1 transposition

Species: Budding yeast (Taxid: 4932)
Factor: CYR1
Manipulation: Loss-of-Function, Mutation, Transposition
Effect:

Transposon-mutagenized CYR1 increases resistance to oxidants and extends chronological lifespan by up to 90%. Stress-resistance transcription factors Msn2/Msn4 and protein kinase Rim15 are required for this lifespan extension [11292860].

Mean: +300

Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

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