Figure 4. Minimal impact of SIR-2.4 on IIS-induced longevity, DAF-16 nuclear localization induced by reduced IIS, and dauer formation.

Study: C. elegans SIRT6/7 homolog SIR-2.4 promotes DAF-16 relocalization and function during stress.
Species: Nematode
Assay: Organismal
Data: genotype treatment mean max

N2 control 15 31
N2 sir-2.4(RNAi) 20 31

daf-2 control 52 93
daf-2 sir-2.4(RNAi) 52 89

ID exp ctr Manipulation intervention mean median max pvalue T Gender epistasis

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