Notes

sex hormone levels decline with aging

inflammation increases with age [65,66].

GH and IGF-1 levels decline with age [63, 64].

Human computers

The human computer

Species categories (models, immortals...

Probabilistic data structures for web crawler

Thyorid Hormone

Some forms of reduced thyroid function tend to associated with increased longevity in a number of species. DR reduces thyroid hormone levels. A predisposition to low thyorid hormone levels seems to be inherited in long-lived families. Thyorid disease-free population of Ashkenazi Jews is characterized with exceptional longevity. Centenarians tend to have higher serum levels of TSH. There is an inverse correlation between FT4 and TSH levels in centenarians. A severe thyroid hypofunction with reduced core body temperature is observed in long-lived Ames dwarf (df/df) and Snell mice and substantially contribute to the remarkable longevity [http://www.thyroidresearchjournal.com/content/5/1/16/abstract].

Testing denigma trunk. The development version of denigma should have sqlite as default database. Crucial missing data entries should be create by fixtures.

Definition of a problem

  • Initial state
  • actions (s) -> {q, q1, q2, q3}
  • result (s,q) -> s'
  • goal test (s) -> T|F

A focus on the upcoming human data is very promising. Still the discoveries made in vitro cellular and with biomedical model organisms should not totally ignore . Interventions that work in multiple model systems, have a huge potential to also influence human aging. Best beat would be to somehow take advantages of both approaches.

Data collection assembly phase.

Science should work hard on defeating aging.


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