- Telomere shortening
- Mitochondrial
- Mutation accumulation
- Senescence gene expression
- Somatic atrophy
a) Mitochondrial apoptosis
b) Nuclear DNA fragmentation
- Sex tissue atrophy
Aging damages
- Cancer-causing nuclear mutation/epimutations
- Mitochondrial mutations
- Intracellular aggregates
- Extracellular aggregates
- Cell loss
- Cell senescence
- Extracellular crosslinks
Tags: theory
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