Denigma Buck Institute Health Extension

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polymorphism factor odds ratio pvalue initial number replication number Population age of cases shorter lived allele longer lived allele study type reference
rs9517320 STK24 — 0.00204 1173 vs 570 — American 85-100 — C Genome-Wide Association Study 22533364
rs3906146 LMX1B 1.23 0.000260059 801 vs 914 — Caucasian Median age 104 A G Genome-Wide Association Study 22279548
rs7914 CBL — 0.69 190 vs 376 — Japanese 95+ — — Candidate Region/Gene 23770741
rs139170 PARVG — 0.00332 1173 vs 570 — American 85-100 — T Genome-Wide Association Study 22533364
rs4751140 EBF3 1.21 0.000268865 801 vs 914 — Caucasian Median age 104 A G Genome-Wide Association Study 22279548
rs2511837 CBL — 0.14 212 vs 398 — Japanese 95+ — — Candidate Region/Gene 23770741
rs1800629 TNF — 1.0 119 vs 118 — Jordanian Mean age 90.2 — — Candidate Region/Gene 20518833
rs4648884 RUNX3 — 0.00992 1173 vs 570 — American 85-100 — T Genome-Wide Association Study 22533364
rs12155014 OGDH 1.12 0.00080402 801 vs 914 — Caucasian Median age 104 G A Genome-Wide Association Study 22279548
rs1800896 IL10 — 0.031 119 vs 118 — Jordanian Mean age 90.2 G A Candidate Region/Gene 20518833
rs739401 CARS — 0.00154 1173 vs 570 — American 85-100 — C Genome-Wide Association Study 22533364
rs10863373 Intergenic 1.01 0.000408144 801 vs 914 — Caucasian Median age 104 C A Genome-Wide Association Study 22279548
rs2075650 APOE — 0.000527 1364 — American, British Age range 50-108; mean age at death 80.2 C T Candidate Region/Gene 22445811
rs1776180 EXO1 — 0.16 206 vs 401 — Japanese 95+ — — Candidate Region/Gene 23770741
marker D4S1564 — — 0.044 308 — European min. age 98 for one sibling. 91+ males, 95+ females — — Genome-Wide Association Study 11526246
rs10256972 C7orf50 — 0.00224 1173 vs 570 — American 85-100 — A Genome-Wide Association Study 22533364
rs2604294 Intergenic 1.33 0.000250017 801 vs 914 — Caucasian Median age 104 A G Genome-Wide Association Study 22279548
rs3764650 ABCA7 — 0.135 1364 — American, British Age range 50-108; mean age at death 80.2 C A Candidate Region/Gene 22445811
rs10937739 PPP2R2C — 0.00404 1173 vs 570 — American 85-100 — T Genome-Wide Association Study 22533364
rs1280396 CGNL1 1.34 0.00099615 801 vs 914 — Caucasian Median age 104 G A Genome-Wide Association Study 22279548
rs610932 MS4A6A — 0.176 1364 — American, British Age range 50-108; mean age at death 80.2 C A Candidate Region/Gene 22445811
rs1815274 JUN — 0.18 212 vs 401 — Japanese 95+ — — Candidate Region/Gene 23770741
rs5771675 FAM19A5 — 0.00985 1173 vs 570 — American 85-100 — A Genome-Wide Association Study 22533364
rs10263457 Intergenic 1.11 0.001203582 801 vs 914 — Caucasian Median age 104 A G Genome-Wide Association Study 22279548
rs3851179 PICALM — 0.227 1364 — American, British Age range 50-108; mean age at death 80.2 G A Candidate Region/Gene 22445811