Denigma Buck Institute Health Extension
Polymorphism: 2 SNPs, not specified





Location: 19q13.2-q13.4

Factor:
- Symbol: PIK3R2
- Name: phosphoinositide-3-kinase, regulatory subunit 2 (beta)
- Entrez ID: 5296
- Ensembl ID: ENSG00000105647

Factors:
  • PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) ( 5296 / ENSG00000105647 )

    • Ethnicity: Caucasian
    Age of cases: 95.3 ± 2.2_x000D_;+M19994.5 ± 2.1_x000D_;mean 97.7, 95– 150

    Statistics
    - Number of cases/controls: 335 vs 603;279 vs 797;383 vs 363 (initial)
    - Significant: No

    Study Design
    - Classifications: No Age Effect
    - Study type: Candidate Region/Gene
    - Technology: In 1st and 2nd Cohort, Two methods: template directed primer extension with fluorescence polarization detection (FP- TDI, AcycloPrime II detection kit, Perkin Elmer, Boston, MA, USA) (Hsu & Kwok, 2003) and SNPstream 48plex (Beckman Coulter, Fullerton

    Reference:
    19489743: Association of common genetic variation in the insulin/IGF1 signaling pathway with human longevity.

    Choice: Curate
    Created: July 2, 2013, 2:47 a.m.
    Updated: Aug. 8, 2014, 1:06 p.m.

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