Polymorphism: 3 SNPs, not specified
Location: 16p13.3
Factor:
- Symbol: PDPK1
- Name: 3-phosphoinositide dependent protein kinase-1
- Entrez ID: 5170
- Ensembl ID: ENSG00000140992
Factors:
PDPK1
3-phosphoinositide dependent protein kinase-1
(
5170
/
ENSG00000140992
)
Ethnicity:
Caucasian
Age of cases: 95.3 ± 2.2_x000D_;+M19994.5 ± 2.1_x000D_;mean 97.7, 95– 146
Statistics
- Number of cases/controls: 331 vs 603;279 vs 797;383 vs 363 (initial)
- Significant: No
Study Design
- Classifications:
No Age Effect
- Study type: Candidate Region/Gene
- Technology: In 1st and 2nd Cohort, Two methods: template directed primer extension with fluorescence polarization detection (FP- TDI, AcycloPrime II detection kit, Perkin Elmer, Boston, MA, USA) (Hsu & Kwok, 2003) and SNPstream 48plex (Beckman Coulter, Fullerton
Reference:
19489743: Association of common genetic variation in the insulin/IGF1 signaling pathway with human longevity.
Choice: Curate
Created: July 2, 2013, 2:47 a.m.
Updated: Aug. 8, 2014, 1:06 p.m.
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