Polymorphism: apoE haplotypes



Variant Type: Haplotype
Location: 19q13.2

Factor:
- Symbol: APOE
- Name: apolipoprotein E
- Entrez ID: 348
- Ensembl ID: ENSG00000130203

Factors:
  • APOE apolipoprotein E ( 348 / ENSG00000130203 )


  • Description:

    ApoE4 found to correlate with MI in Chinese Uygurs; less frequent in the long-lived. Likelihood Ratio Chi2=8.684, ν=2.

    odds_ratio = N/A

    Ethnicity: Chinese
    Age of cases: 90+
    Shorter lived allele: apoE4
    Finding: Positive

    Statistics
    - Number of cases/controls: 35 old vs 71 young vs 54 MI patients (initial)
    - p-value: 0.013
    - Significant: Yes

    Study Design
    - Study type: Candidate Region/Gene
    - Technology: PCR, gel electrophoresis

    Reference:
    11780357: Apolipoprotein E gene polymorphism and its association with human longevity in the Uygur nationality in Xinjiang.

    Choice: Curate
    Created: June 30, 2013, midnight
    Updated: Aug. 8, 2014, 1:05 p.m.

    Edit (Admin) | Delete