Polymorphism: apoE haplotypes
Variant Type: Haplotype
Location: 19q13.2
Factor:
- Symbol: APOE
- Name: apolipoprotein E
- Entrez ID: 348
- Ensembl ID: ENSG00000130203
Factors:
APOE
apolipoprotein E
(
348
/
ENSG00000130203
)
Description:
ApoE4 found to correlate with MI in Chinese Uygurs; less frequent in the long-lived. Likelihood Ratio Chi2=8.684, ν=2.
odds_ratio = N/A
Ethnicity:
Chinese
Age of cases: 90+
Shorter lived allele: apoE4
Finding: Positive
Statistics
- Number of cases/controls: 35 old vs 71 young vs 54 MI patients (initial)
- p-value:
0.013
- Significant: Yes
Study Design
- Study type: Candidate Region/Gene
- Technology: PCR, gel electrophoresis
Reference:
11780357: Apolipoprotein E gene polymorphism and its association with human longevity in the Uygur nationality in Xinjiang.
Choice: Curate
Created: June 30, 2013, midnight
Updated: Aug. 8, 2014, 1:05 p.m.
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