Polymorphism: J mtDNA haplogroup







Description:

Study checked association of mitochondrial haplogroups to longevity. There are many haplogroups. Sig association to longevity was found in mt J haplogroup

gene symbol = mitochondrial haplogroups (invalid literal for int() with base 10: 'N/A')

entrez gene id = N/A (invalid literal for int() with base 10: 'N/A')

Ethnicity: Spaniard
Age of cases: >85 (oldest age group)

Statistics
- Number of cases/controls: 138 vs 138 (initial)
- p-value: 0.027 [0.027]
- Significant: Yes

Study Design
- Classifications: Longevity-Associated
- Technology: PCR amplification of short mtDNA fragments, followed by restriction enzyme analysis (RFLP) and confirmed by HVR-I and HVR-II sequencing

Reference:
18931934: Association of mitochondrial haplogroup J and mtDNA oxidative damage in two different North Spain elderly populations.

Choice: Curate
Created: July 2, 2013, 2:47 a.m.
Updated: Aug. 10, 2014, 12:01 a.m.

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