Polymorphism: DQB1*02;DQB1*03;DQB1*04;DQB1*05;DQB1*06


Variant Type: Haplotype
Location: 6p21.3

Factor:
- Symbol: HLA-DQB1
- Name: major histocompatibility complex, class II, DQ beta 1
- Entrez ID: 3119
- Ensembl ID: ENSG00000179344

Factors:
  • HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 ( 3119 / ENSG00000179344 )


  • Description:

    Only observed a not significant increase in centenarians both of HLA-DQA101,DQB105 and HLA-DQA101, DQB106 haplotypes.

    Ethnicity: Italian
    Age of cases: centenarians
    Finding: Negative

    Statistics
    - Number of cases/controls: 123 vs 92 (initial)
    - Significant: No

    Study Design
    - Classifications: No Age Effect
    - Study type: Candidate Region/Gene
    - Technology: Allele specific PCR products were detected by electrophoresis on 2% agarose

    Reference:
    17714903: Analysis of HLA-DRB1, DQA1, DQB1 haplotypes in Sardinian centenarians.

    Choice: Curate
    Created: July 2, 2013, 2:47 a.m.
    Updated: Aug. 8, 2014, 1:06 p.m.

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