Polymorphism: −1190G/A


Variant Type: SNP
Location: 6p12

Factor:
- Symbol: VEGFA
- Name: vascular endothelial growth factor A
- Entrez ID: 7422
- Ensembl ID: ENSG00000112715

Factors:
  • VEGFA vascular endothelial growth factor A ( 7422 / ENSG00000112715 )

  • Ethnicity: Italian
    Age of cases: 85-99 (mean 89.8±2.8)
    Shorter lived allele: G
    Longer lived allele: A
    Finding: Positive

    Statistics
    - Number of cases/controls: 166 vs 324 (initial)
    - Odds ratio: 1.39
    - p-value: 0.014 [0.014]
    - Significant: Yes

    Study Design
    - Classifications: Longevity-Associated
    - Study type: Candidate Region/Gene
    - Technology: Direct sequencing analysis of PCR fragments using BigDyeTerminatorTM protocol on an automated 3100ABI Prism Genetic Analyzer (Applied Biosystem, Foster City, CA)

    Reference:
    17574707: Role of VEGF gene variability in longevity: a lesson from the Italian population.

    Choice: Curate
    Created: July 2, 2013, 2:47 a.m.
    Updated: Aug. 8, 2014, 1:06 p.m.

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