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Longevity DB
Genetic variants implicated in human longevity.
Polymorphism:
rs3745546
rs3745546
(
SNPedia
|
23andMe
)
Variant Type:
SNP
Location:
19p13.3-p13.2
Factor:
- Symbol:
INSR
- Name:
insulin receptor
- Entrez ID:
3643
- Ensembl ID:
ENSG00000171105
Factors:
INSR
insulin receptor
(
3643
/
ENSG00000171105
)
Ethnicity:
Japanese
Age of cases:
mean age 106.8
Finding:
Negative
Statistics
- Number of cases/controls:
122 vs 122 (initial)
- p-value:
0.168 [0.168]
- Significant:
No
Study Design
- Classifications:
No Age Effect
- Study type:
Candidate Region/Gene
- Technology:
DNA sequencing using the BigDye Terminator cycle sequencing kit and an ABI Prism 3700 DNA analyzer or by real-timepyrophosphate DNA sequencing using a PSQ 96 system
Reference:
15582274: Association analysis between longevity in the Japanese population and polymorphic variants of genes involved in insulin and insulin-like growth factor 1 signaling pathways.
Choice:
Curate
Created:
July 2, 2013, 2:47 a.m.
Updated:
Aug. 8, 2014, 1:05 p.m.
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