Polymorphism: rs5882
rs5882 ( SNPedia | 23andMe )

Variant Type: SNP
Location: 16q13

Factor:
- Symbol: CETP
- Name: cholesteryl ester transfer protein, plasma
- Entrez ID: 1071
- Ensembl ID: ENSG00000087237

Factors:
  • CETP cholesteryl ester transfer protein, plasma ( 1071 / ENSG00000087237 )


  • Description:

    Aim: connection of CVD development with age and CETP polymorphism. Several case-control populations.

    Ethnicity: Ashkenazi Jewish
    Age of cases: 98,2 +/- 5,3
    Shorter lived allele: non-GG
    Longer lived allele: GG
    Finding: Positive

    Statistics
    - Number of cases/controls: 213 vs 258 (initial)
    - Odds ratio: 3.56
    - p-value: 0.001
    - Significant: Yes

    Study Design
    - Classifications: Longevity-Associated
    - Study type: Candidate Region/Gene
    - Technology: PCR

    Reference:
    14559957: Unique lipoprotein phenotype and genotype associated with exceptional longevity.

    Choice: Curate
    Created: June 30, 2013, midnight
    Updated: Aug. 8, 2014, 1:05 p.m.

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