Denigma Buck Institute Health Extension
Polymorphism: I/D (insertion/deletion)



Location: 17q23.3

Factor:
- Symbol: ACE
- Name: angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
- Entrez ID: 1636
- Ensembl ID: ENSG00000159640

Factors:
  • ACE angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 ( 1636 / ENSG00000159640 )


    • Description:

    Deletion = 190 bp (intron 16); Insertion = 490 bp (intron 16)

    Ethnicity: French
    Age of cases: centenarians 100th year or beyond, mean age 103.1

    Statistics
    - Number of cases/controls: 560 vs 560 (initial)
    - p-value: 0.33 [0.33]
    - Significant: No

    Study Design
    - Classifications: No Age Effect
    - Study type: Candidate Region/Gene
    - Technology: PCR and subsequent electrophoretic analysis on a 2 % agarose gel

    Reference:
    11280044: A study of French centenarians: are ACE and APOE associated with longevity?

    Choice: Curate
    Created: July 2, 2013, 2:47 a.m.
    Updated: Aug. 8, 2014, 1:06 p.m.

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