Polymorphism: 3' variable number tandem repeat 3'APOB-VNTR

Location: 2p24-p23

- Symbol: APOB
- Name: apolipoprotein B (including Ag(x) antigen)
- Entrez ID: 338
- Ensembl ID: ENSG00000084674

  • APOB apolipoprotein B (including Ag(x) antigen) ( 338 / ENSG00000084674 )

  • Description:

    Allele nomenclature refers to the number of_x000D_ repeats in the core sequence motif_x000D_. The alleles were grouped into three categories,small (S), medium (M) and large (L). the population sample was subdivided into 7 age-classes_x000D_. Not a simple cases-vs-controls study.As the age increases, there seems to be an increase and later a decrease in allelic frequecy, a parabolic change in frequency. I have no Idea how to curate their findings.

    Ethnicity: Italian

    - Number of cases/controls: 697 (initial)

    Study Design
    - Classifications: No Age Effect
    - Study type: Candidate Region/Gene
    - Technology: Allele classification was performed by using the same allele ladder in each experiment. The ladder was obtained by PCR amplification of reference DNA samples containing 3'APOB-VNTR alleles of known size.

    9759473: Age-related changes of the 3'APOB-VNTR genotype pool in ageing cohorts.

    Choice: Discard
    Created: July 2, 2013, 2:47 a.m.
    Updated: Aug. 8, 2014, 1:06 p.m.

    Edit (Admin) | Delete