Polymorphism: CYP2C19*1 (wt allele) / CYP2C19*2( rs4244285 / rs17878459 )
rs4244285
(
SNPedia |
23andMe
)
rs17878459
(
SNPedia |
23andMe
)
Location: 10q24
Factor:
- Symbol: CYP2C19
- Name: cytochrome P450, family 2, subfamily C, polypeptide 19
- Entrez ID: 1557
- Ensembl ID: ENSG00000165841
Factors:
CYP2C19
cytochrome P450, family 2, subfamily C, polypeptide 19
(
1557
/
ENSG00000165841
)
Description:
The odds ratio is given to poor metabolism
pvalue = 0.1<p<0.2 (invalid literal for float(): 0.10.2)
Ethnicity:
Danish
Age of cases: 95 and over
Statistics
- Number of cases/controls: 239 vs 64 (initial)
- Odds ratio: 1.21
- p-value:
0.2
[0.1<p<0.2]
- Significant: No
Study Design
- Classifications:
No Age Effect
- Study type: Candidate Region/Gene
- Technology: Oligonucleotide ligation assay
Reference:
9754988: Genotypes for the cytochrome P450 enzymes CYP2D6 and CYP2C19 in human longevitY. Role of CYP2D6 and CYP2C19 in longevity.
Choice: Curate
Created: July 2, 2013, 2:47 a.m.
Updated: Aug. 8, 2014, 1:06 p.m.
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