Polymorphism: CYP2C19*1 (wt allele) / CYP2C19*2( rs4244285 / rs17878459 )





rs4244285 ( SNPedia | 23andMe )

rs17878459 ( SNPedia | 23andMe )


Location: 10q24

Factor:
- Symbol: CYP2C19
- Name: cytochrome P450, family 2, subfamily C, polypeptide 19
- Entrez ID: 1557
- Ensembl ID: ENSG00000165841

Factors:
  • CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 ( 1557 / ENSG00000165841 )


  • Description:

    The odds ratio is given to poor metabolism

    pvalue = 0.1<p<0.2 (invalid literal for float(): 0.10.2)

    Ethnicity: Danish
    Age of cases: 95 and over

    Statistics
    - Number of cases/controls: 239 vs 64 (initial)
    - Odds ratio: 1.21
    - p-value: 0.2 [0.1<p<0.2]
    - Significant: No

    Study Design
    - Classifications: No Age Effect
    - Study type: Candidate Region/Gene
    - Technology: Oligonucleotide ligation assay

    Reference:
    9754988: Genotypes for the cytochrome P450 enzymes CYP2D6 and CYP2C19 in human longevitY. Role of CYP2D6 and CYP2C19 in longevity.

    Choice: Curate
    Created: July 2, 2013, 2:47 a.m.
    Updated: Aug. 8, 2014, 1:06 p.m.

    Edit (Admin) | Delete