Polymorphism: apoAIV(360:His)
Location: 11q23
Factor:
- Symbol: APOA4
- Name: apolipoprotein A-IV
- Entrez ID: 337
- Ensembl ID: ENSG00000110244
Factors:
APOA4
apolipoprotein A-IV
(
337
/
ENSG00000110244
)
Description:
The comparison originally included AD patients and healthy aged individuals, but the n=119 refers to the aged individuals only -- I didn't include the AD old in the cases.
Ethnicity:
French
Age of cases: 74.29 ∓ 8.46
Shorter lived allele: ApoAIV-1_x000D_, by the order of the sentence - I'm assuming it's Glutamine = G
Statistics
- Number of cases/controls: 119 (see notes) vs 264 (initial)
- p-value:
0.005
[<0.005]
- Significant: Yes
Study Design
- Classifications:
Longevity-Associated
- Study type: Candidate Region/Gene
Reference:
9533408: Apolipoprotein AIV codon 360 mutation increases with human aging and is not associated with Alzheimer's disease.
Choice: Curate
Created: July 2, 2013, 2:47 a.m.
Updated: Aug. 8, 2014, 1:06 p.m.
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