Polymorphism: ACE genotype




Factor:
- Symbol: ACE
- Name: angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
- Entrez ID: 1639348
- Ensembl ID: ENSG00000159640

Factors:
  • ACE angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 ( 1639348 / ENSG00000159640 )


  • Description:

    These results suggest that neither the ACE nor the APOE gene is significantly associated with longevity in the Korean population, but that the APOE epsilon4 allele is still related with dementia even at age 100 and older.

    Ethnicity: Korean
    Age of cases: Mean age 102
    Finding: Negative

    Statistics
    - Number of cases/controls: 102 vs 7232 (initial)
    - p-value: 0.716 [0.716]
    - Significant: no

    Study Design
    - Classifications: No Age Effect
    - Study type: Candidate Region/Gene
    - Technology:

    Reference:
    12634288: Distributions of ACE and APOE polymorphisms and their relations with dementia status in Korean centenarians.

    Choice: Curate
    Created: July 2, 2013, 2:33 a.m.
    Updated: Aug. 26, 2013, 3:53 p.m.

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