Polymorphism: XRCC3 intron 3 STR
Variant Type: STR
Location: 14q32.3
Factors:
XRCC3
X-ray repair complementing defective repair in Chinese hamster cells 3
(
7517
/
ENSG00000126215
)
Description:
STR length polymorphism at XRCC3 at intron 3. Possibly it`s rs371038395.
Ethnicity:
British
Age of cases: Mean age 70
Shorter lived allele: 15
Longer lived allele: 13
Finding: Positive
Statistics
- Number of cases/controls: 430 (case) vs 290 (initial)
- p-value:
0.0005
[0.425]
- Significant: Yes
Study Design
- Classifications:
No Age Effect
- Study type: Candidate Region/Gene
- Technology: ABI Prism 310 Genetic Analyser
Reference:
16518718: Genotype profiles of loci encoding DNA repair enzymes in newborn and elderly populations: no evidence of association with longevity.
Choice: Clean
Created: July 2, 2013, 2:33 a.m.
Updated: Aug. 8, 2014, 1:05 p.m.
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