Denigma Buck Institute Health Extension
Polymorphism: rs1346044
rs1346044 ( SNPedia | 23andMe )

Variant Type: SNP
Location: 8p12

Factor:
- Symbol: WRN
- Name: Werner syndrome, RecQ helicase-like
- Entrez ID: 7486
- Ensembl ID: ENSG00000165392

Factors:
  • WRN Werner syndrome, RecQ helicase-like ( 7486 / ENSG00000165392 )


    • Description:

    Therefore, we suggest that the analyzed polymorphic variants of the WRN influence neither the rate of aging nor the longevity.

    Trivial name is C1367R.

    Ethnicity: Polish
    Age of cases: Mean age 101.1
    Finding: Negative

    Statistics
    - Number of cases/controls: 149 vs 414 (initial)
    - Significant: No

    Study Design
    - Classifications: No Age Effect
    - Study type: Candidate Region/Gene
    - Technology: PCR

    Reference:
    20855428: Aging is accompanied by a progressive decrease of expression of the WRN gene in human blood mononuclear cells.

    Choice: Clean
    Created: July 1, 2013, 1:04 p.m.
    Updated: Aug. 8, 2014, 1:05 p.m.

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