Polymorphism: --1082G-->A
Location: 1q31-q32
Factor:
- Symbol: IL10
- Name: interleukin 10
- Entrez ID: 3586
- Ensembl ID: ENSG00000136634
Factors:
IL10
interleukin 10
(
3586
/
ENSG00000136634
)
Description:
Applies to males only.
Ethnicity:
Italian
Age of cases: >95
Shorter lived allele: A
Finding: Positive
Statistics
- Number of cases/controls: 109 (oldest old men) vs 263 (healthy controls) (initial)
- p-value:
0.0001
[0.0001]
- Significant: Yes
Study Design
- Classifications:
Longevity-Associated
- Study type: Candidate Region/Gene
- Technology: Taq-polymerase
Reference:
15466015: Opposite effects of interleukin 10 common gene polymorphisms in cardiovascular diseases and in successful ageing: genetic background of male centenarians is protective against coronary heart disease.
Choice: Curate
Created: July 1, 2013, 1:04 p.m.
Updated: Aug. 8, 2014, 1:05 p.m.
Edit
(
Admin) |
Delete