Polymorphism: rs2227956
rs2227956 ( SNPedia | 23andMe )

Variant Type: SNP

Factor:
- Symbol: HSPA1L
- Name: heat shock 70kDa protein 1-like
- Entrez ID: 3305
- Ensembl ID: ENSG00000204390


Description:

"As for T2437C variant, the different allele carriers (2437TT and CC) both had an increased tendency for longevity, especially for the 2437TT carriers (P > 0.01)."

Ethnicity: Chinese
Age of cases: >90
Shorter lived allele: TC
Longer lived allele: TT/CC
Finding: Positive

Statistics
- Number of cases/controls: 191 vs 53 (initial)
- p-value: 0.01 [>0.01]
- Significant: Yes

Study Design
- Classifications: Longevity-Associated
- Study type: Candidate Region/Gene
- Technology: PCR based probes

Reference:
19840767: Interactive association of heat shock protein 70 genes variants with natural longevity in Xinjiang Hetian Uygur ethnicity.

Choice: Curate
Created: July 1, 2013, 1:04 p.m.
Updated: Aug. 8, 2014, 1:05 p.m.

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