Denigma Buck Institute Health Extension
Polymorphism: TGFB1 haplotypes



Location: 19q13.1

Factor:
- Symbol: TGFB1
- Name: transforming growth factor, beta 1
- Entrez ID: 7040
- Ensembl ID: ENSG00000105329

Factors:
  • TGFB1 transforming growth factor, beta 1 ( 7040 / ENSG00000105329 )


    • Description:

    This is an analysis of extended TGF-B1 genotypes in Bulgarians

    Ethnicity: Bulgarian
    Age of cases: Age range: 65-99
    Shorter lived allele: codon 10 C/C, codon 25 G/G; −988 C/C, −800 G/G

    Statistics
    - Number of cases/controls: 60 vs 40 (initial)
    - p-value: 0.05 [0.05]
    - Significant: Yes

    Study Design
    - Classifications: Longevity-Associated
    - Study type: Candidate Region/Gene
    - Technology: PCR-based sequencing

    Reference:
    21299522: 'Immunogenetics of Aging': report on the activities of the 15th International HLA and Immunogenetics Working Group and 15th International HLA and Immunogenetics Workshop.

    Choice: Curate
    Created: July 1, 2013, 1:04 p.m.
    Updated: Aug. 8, 2014, 1:06 p.m.

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