Denigma Buck Institute Health Extension
Polymorphism: indel


Location: 17q23.3

Factor:
- Symbol: ACE1
- Name: angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
- Entrez ID: 1636
- Ensembl ID: ENSG00000159640

Factors:
  • ACE1 angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 ( 1636 / ENSG00000159640 )


    • Description:

    "[T]he frequency of the ACE1D allele (or vice versa ACE1I allele) was comparable between centenarians and middle-aged control subjects..."

    Ethnicity: Italian
    Age of cases: Mean age 100 +/- 2

    Statistics
    - Number of cases/controls: 82 vs 252 (initial)
    - p-value: 0.05 [0.05]
    - Significant: No

    Study Design
    - Classifications: No Age Effect
    - Study type: Candidate Region/Gene
    - Technology: SAS system (Proc-LogXact 5), SAS FREQ procedure (version 8.2), Proc-StatXact (version 4.0.1)

    Reference:
    12954489: Angiotensin I converting enzyme (ACE) gene polymorphism in centenarians: different allele frequencies between the North and South of Europe.

    Choice: Curate
    Created: July 1, 2013, 1:03 p.m.
    Updated: Aug. 8, 2014, 1:06 p.m.

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