Polymorphism: rs1800896 - rs1800629
rs1800896
(
SNPedia |
23andMe
)
rs1800629
(
SNPedia |
23andMe
)
Variant Type: Haplotype
Location: 1q31-q32; 6p21.3
Factor:
- Symbol: IL10
- Name: interleukin 10
- Entrez ID: 3586
- Ensembl ID: ENSG00000136634
Factors:
IL10
interleukin 10
(
3586
/
ENSG00000136634
)
TNFa
tumor necrosis factor
(
7124
/
ENSG00000232810
)
Ethnicity:
Italian
Age of cases: >100
Longer lived allele: GG-GG (only in men)
Finding: Positive
Statistics
- Number of cases/controls: 174 vs 224 (initial)
- p-value:
0.038
[0.038 (only in men)]
- Significant: yes
Study Design
- Classifications:
Longevity-Associated
- Study type: Candidate Region/Gene
- Technology: PCR
Reference:
12676903: Inflammation, genetics, and longevity: further studies on the protective effects in men of IL-10 -1082 promoter SNP and its interaction with TNF-alpha -308 promoter SNP.
Choice: Clean
Created: July 1, 2013, 12:55 p.m.
Updated: Aug. 8, 2014, 1:05 p.m.
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