Denigma Buck Institute Health Extension
Polymorphism: rs4946936
rs4946936 ( SNPedia | 23andMe )

Location: 6q21

Factor:
- Symbol: FOXO3
- Name: forkhead box O3
- Entrez ID: 2309
- Ensembl ID: ENSG00000118689

Factors:
  • FOXO3 forkhead box O3 ( 2309 / ENSG00000118689 )

    • Ethnicity: Chinese
    Age of cases: mean age 102.3
    Shorter lived allele: T
    Longer lived allele: C

    Statistics
    - Number of cases/controls: 761 vs 1056 (initial) | 350 vs 350 (replication)
    - Odds ratio: 1.4
    - p-value: 1.8e-05 [1.8e-05]
    - Significant: yes

    Study Design
    - Classifications: Longevity-Associated
    - Study type: Candidate Region/Gene
    - Technology: Not given

    Reference:
    19793722: Genetic association of FOXO1A and FOXO3A with longevity trait in Han Chinese populations.

    Choice: Curate_Jimi
    Created: July 1, 2013, 12:55 p.m.
    Updated: Aug. 8, 2014, 1:05 p.m.

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