Denigma Buck Institute Health Extension
Polymorphism: rs11039149
rs11039149 ( SNPedia | 23andMe )

Variant Type: SNP
Location: 11p11.2

Factor:
- Symbol: NR1H3
- Name: nuclear receptor subfamily 1, group H, member 3
- Entrez ID: 10062
- Ensembl ID: ENSG00000025434

Factors:
  • NR1H3 nuclear receptor subfamily 1, group H, member 3 ( 10062 / ENSG00000025434 )

    • Ethnicity: Dutch
    Age of cases: 85 years
    Shorter lived allele: haplotype 1
    Longer lived allele: haplotype 2
    Finding: Positive

    Statistics
    - Number of cases/controls: 599 (initial)
    - p-value: 0.015 [0.015]
    - Significant: yes

    Study Design
    - Classifications: Longevity-Associated
    - Study type: Candidate Region/Gene
    - Technology: PCR

    Reference:
    17452725: Liver X receptor alpha associates with human life span.

    Choice: Curate_Jimi
    Created: July 1, 2013, 12:43 p.m.
    Updated: Aug. 8, 2014, 1:05 p.m.

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