Polymorphism: rs429358, rs7412
rs429358, ( SNPedia | 23andMe )
rs7412 ( SNPedia | 23andMe )

Variant Type: SNP
Location: 19q13.2

Factor:
- Symbol: APOE
- Name: apolipoprotein E
- Entrez ID: 348
- Ensembl ID: ENSG00000130203

Factors:
  • APOE apolipoprotein E ( 348 / ENSG00000130203 )


  • Description:

    P value for e4 depletion

    Ethnicity: Irish
    Age of cases: >90
    Shorter lived allele: e4
    Longer lived allele: e2
    Finding: Positive

    Statistics
    - Number of cases/controls: 114 vs 2071 (initial)
    - Odds ratio: 0.43
    - p-value: 0.0006 [0.0006]
    - Significant: Yes

    Study Design
    - Classifications: Longevity-Associated
    - Study type: Candidate Region/Gene
    - Technology: Immunobloting

    Reference:
    11470126: Apolipoprotein E alleles in nonagenarian subjects in the Belfast Elderly Longitudinal Free-living Ageing Study (BELFAST).

    Choice: Curate_Jimi
    Created: July 1, 2013, 12:39 p.m.
    Updated: Aug. 8, 2014, 1:05 p.m.

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