Polymorphism: rs1801133
rs1801133 ( SNPedia | 23andMe )

Location: 1p36.3

Factor:
- Symbol: MTHFR
- Name: methylenetetrahydrofolate reductase (NAD(P)H)
- Entrez ID: 4524
- Ensembl ID: ENSG00000177000

Factors:
  • MTHFR methylenetetrahydrofolate reductase (NAD(P)H) ( 4524 / ENSG00000177000 )


  • Description:

    in females

    Ethnicity: Ashkenazi Jewish
    Age of cases: 75
    Shorter lived allele: T
    Longer lived allele: C
    Finding: Positive

    Statistics
    - Number of cases/controls: 224 vs 441 (initial)
    - Odds ratio: 6.001
    - p-value: 0.014 [0.014]
    - Significant: Yes

    Study Design
    - Classifications: Longevity-Associated
    - Study type: Candidate Region/Gene
    - Technology: ABI SNaPshot kit

    Reference:
    15621215: Candidate genes associated with ageing and life expectancy in the Jerusalem longitudinal study.

    Choice: Curate_Jimi
    Created: July 1, 2013, 12:37 p.m.
    Updated: Aug. 8, 2014, 1:05 p.m.

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