Denigma Buck Institute Health Extension
Polymorphism: APOA1-MspI-RFLP A/P alleles




Location: 11q23-q24

Factor:
- Symbol: APOA1
- Name: apolipoprotein A-I
- Entrez ID: 335
- Ensembl ID: ENSG00000118137

Factors:
  • APOA1 apolipoprotein A-I ( 335 / ENSG00000118137 )


    • Description:

    Only significant in males

    Ethnicity: Italian
    Age of cases: median age 101
    Shorter lived allele: A
    Longer lived allele: P

    Statistics
    - Number of cases/controls: 413 vs. 571 (initial)
    - p-value: 0.045 [0.045]
    - Significant: Yes

    Study Design
    - Classifications: Longevity-Associated
    - Study type: Candidate Region/Gene
    - Technology: Not given

    Reference:
    12556235: The study of APOA1, APOC3 and APOA4 variability in healthy ageing people reveals another paradox in the oldest old subjects.

    Choice: Curate_Emily
    Created: July 1, 2013, 10:47 a.m.
    Updated: Aug. 8, 2014, 1:05 p.m.

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