Denigma Buck Institute Health Extension
Polymorphism: APOE polymorphism



Variant Type: Haplotype
Location: 19q13.2

Factor:
- Symbol: APOE
- Name: apolipoprotein E
- Entrez ID: 348
- Ensembl ID: ENSG00000130203

Factors:
  • APOE apolipoprotein E ( 348 / ENSG00000130203 )

    • Ethnicity: Finn
    Age of cases: Mean age 97.5
    Shorter lived allele: e4
    Longer lived allele: e2
    Finding: Positive

    Statistics
    - Number of cases/controls: 291 vs 589 (initial)
    - p-value: 0.0001 [0.0001]
    - Significant: Yes

    Study Design
    - Classifications: Longevity-Associated
    - Study type: Candidate Region/Gene
    - Technology: PCR

    Reference:
    16487435: Apolipoprotein E genotype is related to plasma levels of C-reactive protein and lipids and to longevity in nonagenarians.

    Choice: Clean
    Created: July 1, 2013, 10:47 a.m.
    Updated: Aug. 8, 2014, 1:05 p.m.

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