Polymorphism: rs1805097
rs1805097 ( SNPedia | 23andMe )

Location: 13q34

Factor:
- Symbol: IRS2
- Name: insulin receptor substrate 2
- Entrez ID: 8660
- Ensembl ID: ENSG00000185950

Factors:
  • IRS2 insulin receptor substrate 2 ( 8660 / ENSG00000185950 )

  • Ethnicity: Italian
    Age of cases: 85-100 years old
    Shorter lived allele: non-AA
    Longer lived allele: AA

    Statistics
    - Number of cases/controls: 144 vs 418 (initial)
    - Odds ratio: 2.03
    - p-value: 0.0003 [0.0003]
    - Significant: Yes

    Study Design
    - Classifications: Longevity-Associated
    - Study type: Candidate Region/Gene
    - Technology: PCR-RFLP

    Reference:
    19887537: The IRS2 Gly1057Asp variant is associated with human longevity.

    Choice: Curate_Emily
    Created: July 1, 2013, 10:42 a.m.
    Updated: Aug. 8, 2014, 1:05 p.m.

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