Denigma Buck Institute Health Extension
Polymorphism: rs1799889
rs1799889 ( SNPedia | 23andMe )

Variant Type: SNP
Location: 7q22.1

Factor:
- Symbol: SERPINE1
- Name: serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
- Entrez ID: 5054
- Ensembl ID: ENSG00000106366

Factors:
  • SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 ( 5054 / ENSG00000106366 )


    • Description:

    "The results of this study are not suggestive of an important contribution of the PAI-1 genotype on total mortality."

    Trivial name is -675 A/G 4G/5G

    Ethnicity: German
    Age of cases: mean age=86.1 years
    Finding: Negative

    Statistics
    - Number of cases/controls: 205 cases (initial)
    - Significant: No

    Study Design
    - Classifications: No Age Effect
    - Study type: Candidate Region/Gene
    - Technology: PCR LightCycler (Roche)

    Reference:
    11485022: The plasminogen activator inhibitor 1 4G/5G polymorphism is not associated with longevity: a study in octogenarians.

    Choice: Clean
    Created: July 1, 2013, 10:06 a.m.
    Updated: Aug. 8, 2014, 1:05 p.m.

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