Polymorphism: rs1805415
rs1805415
(
SNPedia |
23andMe
)
Location: 1q41-q42
Factor:
- Symbol: PARP1
- Name: poly (ADP-ribose) polymerase 1
- Entrez ID: 142
- Ensembl ID: ENSG00000143799
Factors:
PARP1
poly (ADP-ribose) polymerase 1
(
142
/
ENSG00000143799
)
Ethnicity:
African American,
Caucasian
Shorter lived allele: G,C
Longer lived allele: T
Statistics
- Number of cases/controls: 479 vs 900 (initial)
| 388 vs 364 (replication)
- Odds ratio: 0.66
- p-value:
0.001
[0.001]
- Significant: Yes
Study Design
- Classifications:
Longevity-Associated
- Study type: Candidate Region/Gene
- Technology: TagSNP genotyping, Sequenom MASSarray
Reference:
19249341: Inflammation and stress-related candidate genes, plasma interleukin-6 levels, and longevity in older adults.
Choice: Curate_Johnny
Created: July 1, 2013, 10:04 a.m.
Updated: Aug. 8, 2014, 1:05 p.m.
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